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Healthcare
The combination of modern separation methods with mass spectrometry has born fruit
in the development of an independent method for the analysis of cholesterol in serum
(to within 1% relative). Accurate cholesterol measurements are important not only for
effective healthcare, but also for their economic impact on the health service. These
new measurement systems, developed at LGC, will also provide improved reference
materials to foster the sound use of measuring instruments in local health centres
and hospitals. The most recent technology has been developed to monitor the blood of
patients, for very low levels of the metals used in artificial hip and knee
replacement cases. In this context, novel and direct analysis of whole blood was able
to monitor the concentrations of the key metals (e.g. Cr, Co, Ni and Ti) used in the
artificial joints.
Recent Publications
| 1. |
Development of a routine method for the determination of Cr, Co, Ni and Mo in whole blood, by magnetic sector ICP-MS with particular relevance to patients with total hip arthroplasty. Clin. Chem, 47, 275 (2001)
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| 2. |
The Analysis of Whole Blood for Trace Metals Using a Double Focusing Magnetic Sector ICP-MS Instrument, in Plasma Source Mass Spectrometry - New Developments & Applications, edited by G Holland & Scott D Tanner, RSC (1999).
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Conference Proceedings
| 1. |
The analysis of whole blood for trace metals using a double focussing magnetic sector instrument. 6th International conference on plasma source mass spectrometry, Durham, Sept (1998).
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