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12-Jan-2006 - LGC participates in EPSRC Think Crime Programme

LGC is pleased to announce its participation in a research project funded at Southampton University under the EPSRC Think Crime Programme, entitled ´Simple, robust and very rapid DNA profiling Crime Feasibility Study´

The work, undertaken within Professor Tom Brown’s group, will look at the ways in which LGC´s HyBeacons® DNA probe technology, already established for single nucleotide polymorphisms (SNPs) analyses in both low a high throughput configurations at LGC, can be further developed for the specific requirements of forensic analysis. It is hoped that it will enable certain types of forensic analysis to be undertaken away from the specialist analytical laboratory in order to confirm an individual’s identity or relevance to an investigation before their release from custody. This feasibility study has been featured in New Scientist, issue 14 January 2006.

HyBeacon® probes were developed at LGC in response to the requirement to identify key genetic differences between individuals and have unique characteristics that make them suitable for very rapid diagnostic and point-of-care applications. To date, HyBeacon assays have been developed for use in genetic medical testing to determine the ability of an individual to derive therapeutic value from certain prescribed drugs and for the identification of the polymorphism linked to deep vein thrombosis. Most recently, in association with the Institute of Psychiatry at King´s College London, LGC´s HyBeacons® technology has enabled the development of a pharmacogenetic screening service which can predict whether a patient with schizophrenia will respond positively to the antipsychotic drug clozapine.

In December 2004, LGC granted its first HyBeacons® licence to Osmetech plc, for use in medical genetic test applications for analyte specific reagents that indicate inherited genetic traits. LGC continues to advance its HyBeacons® technology, developed with DTI support under the LINK Analytical Biotechnology programme, across the spectrum of applications for which rapid point-of-care testing is in demand.


Notes to Editors