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Pharmaceutical analytical testing services

Technology

LGC is equipped with state-of-the-art instrumentation for complex and high accuracy analysis, and maintains close links with instrument suppliers and the science base to ensure early adoption of new technology. Our members of staff have, between them, wide-ranging, specialist and in-depth analytical experience. The technologies used at LGC include, but are not limited to:

Advanced sample preparation

  • Solvent Extraction including Automated Solvent Extraction (ASE)
  • Soxhlet and Soxtect
  • Solid phase extraction
  • Microwave

Separation science

  • High Performance Liquid Chromatography (HPLC) coupled to UV, light scattering
  • Gas Chromatography (GC) with Flame Ionisation (FID), Nitrogen Phosphorus (NPD) and Electron Capture (ECD) detection
  • Head Space Gas Chromatography
  • Capillary Electrophoresis (CE) coupled to UV, Fluorescence
  • Liquid Chromatography-Mass Spectrometry (LC-MS)
  • LC-MSn
  • Gas chromatography-Mass Spectrometry (GC-MS)
  • Gel Permeation Chromatography (GPC)

Advanced Mass spectrometry

  • Capillary Electrophoresis-Mass Spectrometry (CE-MS)
  • Liquid Chromatography-Tandem Mass Spectrometry (LC-MS-MS)
  • 2D Gas chromatography Time-of flight Mass Spectrometry (GC-TOF-MS)
  • 2D Liquid Chromatography-Tandem Mass Spectrometry (LC-MS-MS)
  • Liquid Chromatography – Quadrapole Time-of-Flight Mass Spectrometry (LC-QTOF-MS)
  • Matrix Assisted Laser Desorption Ionisation Time of Flight MS (MALDI-TOF-MS)
  • Fourier Transform Ion Cyclotron Resonance Mass Spectrometry (FT-ICR-MS)

Spectroscopy

  • Fourier Transform-Infra Red (FT-IR)
  • Raman
  • Ultraviolet (UV)
  • Fluorescence
  • Nuclear Magnetic Resonance (NMR)

Particle characterisation

  • Particle size (Dry and Wet systems)
  • Optical microscopy
  • Scanning Electron Microscopy (SEM)
  • Surface area determination
  • Porosimetry
  • Density

Microscopic imaging

  • High resolution SEM (Field emission)
  • Energy dispersive X-Ray detection
  • Backscattered electron detection
  • FT-IR micro spectrometry
  • Raman micro spectrometry
  • Optical microscopy / Image analysis

Morphology and thermal analysis

  • X-ray Diffraction (XRD)
  • Differential Scanning Calorimetry (DSC)
  • Thermogravimetric analysis (TGA)
  • Sorption studies
  • Moisture content

Inorganic analysis

  • Inductively Coupled Plasma (ICP) with Optical Emission Spectroscopy (OES)
  • Inductively Coupled Plasma (ICP) with MS detection,
  • Atomic Absorption (AA)
  • Graphite Furnace Atomic Absorption (GF-AA)
  • X-Ray Fluorescence (XRF)
  • LC/GC ICP-MS

Organic Microanalysis

  • Carbon Hydrogen Nitrogen analysis (CHN)
  • Low level Nitrogen, Sulphur and Chlorine

Measurement of ions in solution

  • Electrochemical methods
  • Ion chromatography

Classical Analysis

  • Karl Fischer
  • Titrimetry
  • Wet Chemical Analysis
  • Colorimetry

 

For further information, contact

Email: pharmaInfo@lgc.co.uk 

LGC, The Heath Business Park, Runcorn, Cheshire WA7 4QX,  UK

Tel: +44 (0)1928 515163

Fax: +44 (0)1928 500125

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