Science & innovation
Cell biology
Applications
Tissue engineering
Novel quantitative cell imaging to improve cell quality
in tissue engineered products
Tissue engineering is an emerging healthcare technology which
uses cells, engineering and materials to manufacture functional
replacement tissues which can be used in clinical applications. As
with any pioneering new technology, regulation is critical for
product quality, safety and development. However the novel aspects
that make the future of tissue engineering so promising also make
complying with regulations more challenging. The European Medicines
Agency (EMA) guidelines require cells to meet a minimum quality for
market authorisation. However, making even routine cell
measurements, such as viability assessment, proves challenging in
the complex environment contained within a tissue engineered
product. This is because the cells are often manufactured in a
3-dimensional (3D) biomaterial matrix which is not compatible with
standard measurement assays.
LGC scientists, in collaboration with leading tissue engineering
companies, have developed a rapid, quantitative imaging approach to
measure the quality of cells in tissue engineered products in order
to improve manufacturing, storage and transportation processes.
Resources
Case
study - Life through a lens – novel quantitative cell
imaging
Contact details
+44 (0)20 8943 8983
measurement@lgc.co.uk
General:
+44 (0)20 8943 7000
info@lgc.co.uk
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