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Analytical services
Contamination in the pharmaceutical sector
Contamination can occur at any stage of
product manufacture and storage and can arise from the raw
materials, cleaning materials, chemicals or equipment used in
production, packaging or from degradation during storage. It can be
inorganic or organic in nature and in solid or liquid form.
Typical examples may include:
- Degradation of Active Pharmaceutical
Ingredients (API) or excipients
- Precipitation from solution
- Change of polymorphic form or presence of other
polymorphic forms
- Residual solvents
- Discoloration
- Processing contaminants e.g. glass, fibres,
seals, coatings etc.
In many cases, the contamination is due to visible or
sub-visible particulate matter, and we are able to identify and
count such particles.(LINK)
Scientists at LGC have extensive experience in applying a wide
variety of techniques in order to solve complex contamination
problems in the pharmaceutical and healthcare sector.
The techniques that we employ include:
- Optical microscopy with image analysis
- Scanning Electron Microscope (SEM) fitted
with EDX for qualitative elemental analysis
- High Resolution SEM with Field Emission
- FTIR and Raman microscopy
- NMR
- X-Ray Diffraction
- GC/MS
- HPLC
- Thermal analysis
Our Sectors
More about our work in the Pharmaceuticals sector
Contact details
For more information, contact
Madhu Mittra
+44 (0)20 8943 7580
pharmaceuticals@lgcgroup.com
General:
+44 (0) 208 943 7000
info@lgc.co.uk